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Grants to USA, Canada, and International Researchers for Research Projects Related to Duchenne Muscular Dystrophy

Research Grant - Global Awards for Research in DMD-AWARD


GrantWatch ID#

Funding Source
Array ( [0] => American Samoa (USA); [1] => Guam (USA); [2] => Puerto Rico (USA); [3] => Virgin Islands (USA); [4] => Northern Mariana Islands (USA); )

Geographic Focus
USA Territories: American Samoa (USA);   Guam (USA);   Puerto Rico (USA);   Virgin Islands (USA);   Northern Mariana Islands (USA);
USA Compact Free Associations:The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)
International, Israel and Canada.

Important Dates
Deadline: 07/10/23 Save

Grant Description
Grants to USA, Canada, and International researchers associated with institutions for research projects related to Duchenne muscular dystrophy. Funding is intended to support studies that involve basic and clinical research of gene therapy for DMD. The purpose of the program is to advance the science, treatment, and assessment of DMD.

Clinical Area

  • Duchenne muscular dystrophy (DMD)

Area of Interest for this RFP:

  • Research projects that will be considered for support include the following basic and clinical research of gene therapy for DMD:
    • What is the prevalence of Adeno-associated virus (AAV) neutralizing antibodies within a DMD patient population
    • Strategies that can circumvent pre-existing neutralizing antibodies (nABs) to AAV that may allow future re-dosing or enabling eligibility for gene therapy for those patients with pre-existing nABs
    • What mechanism underpin the immunologic adverse effects of gene therapy and strategies that can be used to mitigate the risk and treat adverse responses
    • What mechanisms influence the durability of response to gene therapy and what factors predict response to guide decision making
    • Innovative and novel approaches that can support assessment and long-term follow-up for those DMD boys receiving gene therapy
    • Establish Minimal Clinically Important Difference (MCID) for relevant assessment used in DMD
    • Identify novel risk factors and potential management strategies for rapid DMD disease progression, cognitive impairment or development of other co-morbidities
    • Understand and predict response to treatment and the disease course of DMD
    • Develop and/or validate diagnostic, prognostic or response biomarkers in DMD
    • Understanding the clinical, economic and societal burden of DMD
    • How changes in motor function relate to changes in DMD patient and caregiver quality of life and/or activities of daily living
    • Treatment patterns in DMD, including the evolving use of steroids, exon-skippers, and gene therapy


Additional Eligibility Criteria
Geographic Scope:
• Global

Applicant Eligibility Criteria
• Only organizations are eligible to receive grants, not individuals or medical practice groups.
• The applicant (PI) must have a medical or postdoctoral degree (MD, PhD, or equivalent), an advanced nursing degree (BSN with a MS/PhD), or a degree in Pharmacy, Physiotherapy, or Social Work.
• Applicant must be affiliated with a host institution.
• Both early career and experienced investigators are encouraged to apply and consideration will be given to all proposals meeting the selection criteria.

Pre-Application Information
• RFP Release Date: 4/27/2023
• Full Proposal Due Date: 7/10/2023
• Review of Full Proposals by ERP: August 2023
• Anticipated Full Proposal Notification Date: September 2023
• Grants will be distributed following a fully executed agreement and submission of Final Protocol, documentation of IRB/IEC approval, regulatory approval (if applicable), exemption or waiver.

Number of Grants

Estimated Size of Grant
Individual projects requesting up to $100,000 will be considered.

Contact Information
Apply online:

If you have questions regarding this RFP, please direct them in writing to the Grant Officer, Amanda Stein (, with the subject line 2023 RD G DMD RESEARCH

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