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Cooperative Agreement to a USA IHE, Agency, Tribe, Tribal Organization,
or CBO to Expand a Research Program on Adolescent Health

MCH Adolescent and Young Adult Health Research Network (AYAH-RN)

Agency Type:


Funding Source:

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US Department of Health and Human Services (DHHS) - Health Resources and Services Administration (HRSA) - Maternal and Child Health Bureau (MCHB) - Office of Epidemiology and Research

Conf. Date:


Deadline Date:

03/15/22 11:59 PM


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Cooperative agreement to a USA institution of higher education, nonprofit agency, tribe, tribal organization, or CBO to expand a national research program that addresses health issues for adolescents and young adults. Required registrations may take several weeks to complete.

This notice announces the opportunity to apply for funding under the MCH Adolescent and Young Adult Health Research Network (AYAH-RN). The purpose of this program is to grow and extend a national, multi-site, collaborative Research Network that will accelerate the translation of research into Maternal and Child Health (MCH) AYA practice; promote scientific collaboration; and develop additional research capacity in the AYA health field (serving adolescents and young adults ages 10–25). The Research Network will provide support for the establishment and maintenance of critical infrastructure necessary for efficient leadership, coordination, and translation of research on emergent and persistent public health challenges, including poorer outcomes among underserved and disadvantaged AYA populations.

The AYAH-RN will:

  • Grow and extend a national, multi-site, collaborative Research Network that will accelerate the translation of research into MCH AYA practice;
  • Improve access to, use of, and quality of AYA preventive health care, including well-visits and the integration of mental, emotional, and behavioral health into primary care and/or school-based settings;
  • Address current trends among AYA and their implications for health care services delivery regarding topics such as: alignment with a changing health care system, technological advances, the changing face of substance use, demographic trends in the racial and ethnic composition of AYA populations, and the long-term impacts of COVID-19, including vaccine hesitancy and the mental, emotional, and behavioral health of AYA populations;
  • Develop innovative, empirically sound strategies for increasing equity in health and safety outcomes for AYA focusing on underserved populations; 
  • Coordinate a plan to enhance the research training and mentorship of diverse emerging MCH investigators through the use of innovative mentorship/research experiences and manuscript development;  Improve health outcomes in the transition from adolescence to young adulthood; and
  • Accelerate the dissemination and translation into practice of new and emerging research findings relating to AYA health from developmental neuroscience and other relevant fields, such as the science of puberty, prevention, and mental, emotional, and behavioral health.

For award details, see page 10 of the NOFO document below. 

GrantWatch ID#:

GrantWatch ID#: 177253

Estimated Total Program Funding:


Number of Grants:

Estimated Number and Type of Award(s): Up to one cooperative agreement

Estimated Size of Grant:

Up to $450,000 per year subject to the availability of appropriated funds

Term of Contract:

Period of Performance: September 1, 2022 through August 31, 2027 (5 years)

Additional Eligibility Criteria:

Eligibility is limited to domestic public or non-profit institutions of higher learning and public or private non-profit agencies engaged in research or in programs relating to maternal and child health and/or services for children with special health care needs. See 42 CFR § HRSA-22-077 ii 51a.3(b). Domestic faith-based and community-based organizations, tribes, and tribal organizations are eligible to apply.

Pre-proposal Conference:

HRSA has scheduled the following technical assistance:

Day and Date: Monday, January 3, 2022
Time: 1–2 p.m. ET
Call-In Number: 1-833-568-8864
Participant Code: 77488438

In an attempt to more effectively utilize our TA webinar time, if you have questions about the NOFO, please send them prior to the webinar via email to Evva Assing-Murray.

HRSA will record the webinar and make it available approximately 2 weeks after the webinar at:

Pre-Application Information:

The due date for applications under this NOFO is March 15, 2022 at 11:59 p.m. ET. HRSA suggests submitting applications to at least 3 calendar days before the deadline to allow for any unforeseen circumstances.

Currently, the registration process requires information in three separate systems:
• Dun and Bradstreet (
• System for Award Management (SAM) ( Knowledge Base)
• (

Ensure your and registrations and passwords are current immediately! HRSA will not approve deadline extensions for lack of registration. Registration in all systems may take up to 1 month to complete.

View this opportunity on

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

You may request additional information and/or technical assistance regarding business, administrative, or fiscal issues related to this NOFO by contacting:

Tonya Randall
Grants Management Specialist
Division of Grants Management Operations, OFAM
Health Resources and Services Administration
5600 Fishers Lane, Mailstop 10SWH03
Rockville, MD 20857
Telephone: (301) 594-4259
Fax: (301) 443-6343

You may request additional information regarding the overall program issues and/or technical assistance related to this NOFO by contacting:

Evva Assing-Murray, PhD and Lisa Hund, MPH
Program Officers, Division of Research, Office of Epidemiology and Research
Attn: MCH Adolescent and Young Adult Health Research Network (AYAH-RN)
Maternal and Child Health Bureau
Health Resources and Services Administration
5600 Fishers Lane
Rockville, MD 20857
Telephone: (301) 594-4113 and (301) 945-3075
Email: and

CFDA Number:


Funding or Pin Number:


URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

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